S-phase and DNA-damage checkpoints: a tale of two yeasts

Curr Opin Cell Biol. 1996 Dec;8(6):781-7. doi: 10.1016/s0955-0674(96)80078-0.


Many genes required for the S-phase and DNA-damage checkpoints have been identified in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe. This year many checkpoint genes have been sequenced, providing new information about the mechanism of checkpoint control. Several of these genes are conserved between the two yeasts but others are species-specific.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Cell Division / physiology
  • DNA Damage / physiology*
  • DNA, Fungal / physiology*
  • S Phase / physiology*
  • Saccharomyces cerevisiae / cytology*
  • Saccharomyces cerevisiae / genetics
  • Schizosaccharomyces / cytology*
  • Schizosaccharomyces / genetics
  • Species Specificity


  • DNA, Fungal