ATP transport and ABC proteins

Chem Biol. 1996 Sep;3(9):703-6. doi: 10.1016/s1074-5521(96)90244-6.

Abstract

ATP can be exported into the extracellular space, where it has important biological effects. Recent evidence shows that direct ATP export across the plasma membrane is associated with the presence of ABC proteins. Do the ABC proteins pump ATP as well as their other substrates, and if so, why?

Publication types

  • Review

MeSH terms

  • ATP Binding Cassette Transporter, Subfamily B, Member 1 / metabolism
  • ATP-Binding Cassette Transporters / metabolism*
  • Adenosine Triphosphate / metabolism*
  • Animals
  • Biological Transport / physiology
  • CHO Cells
  • Cell Membrane / chemistry
  • Cell Membrane / metabolism
  • Cricetinae
  • Models, Biological

Substances

  • ATP Binding Cassette Transporter, Subfamily B, Member 1
  • ATP-Binding Cassette Transporters
  • Adenosine Triphosphate