Exercise-induced ventricular tachycardia without demonstrable heart disease in childhood

Acta Paediatr Jpn. 1996 Oct;38(5):495-9. doi: 10.1111/j.1442-200x.1996.tb03533.x.


Exercise-induced ventricular tachycardia (VT) without demonstrable heart disease was studied in pediatric patients. The study population consisted of 17 patients aged 5-14 years (average 9.1 years), who demonstrated reproducible VT during or immediately after exercise testing using a treadmill. The main reasons for the exercise testing were episodes of exercise-related syncope in two patients, exercise-related palpitation in seven and evaluation of sporadic ventricular premature contraction (VPC) in eight. Of the eight patients in the asymptomatic group, two developed sustained VT and the other six had non-sustained VT. Of the nine patients in the symptomatic group, six developed sustained VT. Verapamil produced a good response in seven of 14 patients, and propranolol in six. None of the patients died during the follow-up period, an average of 59.6 months. In four patients, both VT and VPC disappeared, not only on exercise testing, but also on Holter electro-cardiograms, so the anti-arrhythmic agents were discontinued. One patient had syncope and convulsion caused by rapid bidirectional VT in the follow-up period. It was concluded that the prognosis of exercise-induced VT without demonstrable heart disease in children is relatively benign, but careful follow-up is required.

MeSH terms

  • Adolescent
  • Age Factors
  • Anti-Arrhythmia Agents / therapeutic use
  • Child
  • Electrocardiography, Ambulatory
  • Exercise Test
  • Exercise*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Prognosis
  • Propranolol / therapeutic use
  • Tachycardia, Ventricular / diagnosis
  • Tachycardia, Ventricular / drug therapy
  • Tachycardia, Ventricular / etiology*
  • Verapamil / therapeutic use


  • Anti-Arrhythmia Agents
  • Propranolol
  • Verapamil