Spasmodic dysphonia symptoms as initial presentation of amyotrophic lateral sclerosis

J Voice. 1996 Dec;10(4):362-7. doi: 10.1016/s0892-1997(96)80028-2.


A patient initially diagnosed with adductor-type spasmodic dysphonia was referred for botulinum toxin (Botox) injections, but found on subsequent evaluation to have amyotrophic lateral sclerosis, and therefore Botox was not administered. This unique case underscores the need to delay botulinum toxin treatments in any patient with recent onset symptoms, and to obtain thorough motor speech and voice, otolaryngologic, and neurologic evaluation in all patients prior to consideration for injection.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Amyotrophic Lateral Sclerosis / complications*
  • Amyotrophic Lateral Sclerosis / physiopathology
  • Botulinum Toxins / therapeutic use
  • Deglutition Disorders / diagnosis
  • Deglutition Disorders / etiology
  • Female
  • Fluoroscopy
  • Humans
  • Phonetics
  • Vocal Cords / physiopathology
  • Voice Disorders / complications*
  • Voice Disorders / diagnosis*
  • Voice Disorders / drug therapy


  • Botulinum Toxins