Endoscopic sinus surgery in the treatment of cystic fibrosis with nasal polyposis

Laryngoscope. 1996 Dec;106(12 Pt 1):1540-4. doi: 10.1097/00005537-199612000-00019.


We have performed endoscopic sinus surgery on 46 patients with chronic, polypoid rhinosinusitis since 1989. Follow-up ranged from 1 month to 6 years (mean, 28.2 months). Overall, our patients had a 50% chance either of their symptoms returning to preoperative severity or of undergoing a second endoscopic sinus procedure, by 18 to 24 months of postoperative follow-up. Patients with predominantly infective symptoms of mucopurulent rhinorrhea and pain had a significantly better outcome than those with predominantly nasal blockage. The chance of the former group of patients suffering symptom deterioration back to the preoperative state or undergoing a second endoscopic sinus operation was 37% of that of the latter group. The extent of disease on computed tomography scan had no relation to outcome.

MeSH terms

  • Adult
  • Chronic Disease
  • Cystic Fibrosis / complications*
  • Endoscopy*
  • Female
  • Humans
  • Male
  • Nasal Polyps / etiology
  • Nasal Polyps / surgery*
  • Prospective Studies
  • Recurrence
  • Sinusitis / etiology
  • Sinusitis / surgery*