Central venous thrombosis (CVT) and pulmonary embolism (PE) are complications that have been reported in association with the use of venous-peritoneal shunts (Le Veen). CVT usually develops around the proximal end of the catheter; the clinical course is varied and usually requires venous imaging to confirm the diagnosis. We present a case of CVT associated with PE, in which the thrombus was located in the right ventricular cavity (distal to the catheter tip). Two-dimensional transesophageal echocardiography was used for diagnosis and follow-up.