An engineered penicillin acylase with altered surface charge is more stable in alkaline pH

Ann N Y Acad Sci. 1996 Oct 12:799:61-4. doi: 10.1111/j.1749-6632.1996.tb33178.x.
No abstract available

MeSH terms

  • Bacterial Proteins / chemistry
  • Escherichia coli / enzymology
  • Hydrogen-Ion Concentration
  • Models, Molecular
  • Penicillin Amidase / chemistry*
  • Protein Denaturation
  • Protein Engineering
  • Protein Structure, Tertiary
  • Surface Properties

Substances

  • Bacterial Proteins
  • Penicillin Amidase