Granulomatous hypophysitis associated with Takayasu's disease

Clin Endocrinol (Oxf). 1996 Oct;45(4):499-503. doi: 10.1046/j.1365-2265.1996.8110821.x.


We report a case of Takayasu's disease, presenting with symptoms of fever, anaemia, elevated erythrocyte sedimentation rate, anterior pituitary failure and mild diabetes insipidus. A pituitary mass with suprasellar extension mimicking a pituitary adenoma was found, and histological examination revealed granulomatous hypophysitis. The diagnosis of Takayasu's disease was established after the development of a multiple arterial occlusive disease. We suggest that Takayasu's disease should be considered in the differential diagnosis of granulomatous hypophysitis of unknown origin.

Publication types

  • Case Reports

MeSH terms

  • Blood Sedimentation
  • Granuloma / pathology
  • Humans
  • Inflammation
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Pituitary Gland / pathology*
  • Pituitary Gland / surgery
  • Takayasu Arteritis / pathology*
  • Takayasu Arteritis / surgery