Genetic heterogeneity of HIV type 1 in Russia: identification of H variants and relationship with epidemiological data

A Bobkov; R Cheingsong-Popov; L Selimova; E Kazennova; N Karasyova; A Kravchenko; N Ladnaya; V Pokrovsky; J Weber

doi:10.1089/aid.1996.12.1687

Genetic heterogeneity of HIV type 1 in Russia: identification of H variants and relationship with epidemiological data

AIDS Res Hum Retroviruses. 1996 Dec 10;12(18):1687-90. doi: 10.1089/aid.1996.12.1687.

Authors

A Bobkov¹, R Cheingsong-Popov, L Selimova, E Kazennova, N Karasyova, A Kravchenko, N Ladnaya, V Pokrovsky, J Weber

Affiliation

¹ D.I. Ivanovsky Institute of Virology, Moscow, Russia.

PMID: 8959244
DOI: 10.1089/aid.1996.12.1687

Abstract

HIV-genetic subtypes were analyzed in 130 subjects from the Russian Federation, by the HMA technique. Six subtypes were identified in heterosexuals, including A, B, C, D, G, and H; however, homosexual men were infected predominantly with the B subtype (33 of 35). The subtype A isolates were found in population of intravenous drug users. HMA successfully identifies 128/130 DNA samples; the phylogenetic analysis of the V1/V5 gp120 encoding region derived from another two samples demonstrated that these isolate belong to subtype H.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Base Sequence
DNA, Viral
Female
Genetic Variation*
HIV Envelope Protein gp120 / genetics*
HIV Infections / epidemiology
HIV Infections / virology*
HIV-1 / classification
HIV-1 / genetics*
HIV-1 / isolation & purification
Humans
Infant
Male
Molecular Sequence Data
Phylogeny
Russia / epidemiology
Sequence Homology, Nucleic Acid

Substances

DNA, Viral
HIV Envelope Protein gp120

Associated data

GENBANK/U33104
GENBANK/U33105
GENBANK/U33106
GENBANK/U33107
GENBANK/U33108