CD40lbase: a database of CD40L gene mutations causing X-linked hyper-IgM syndrome

Immunol Today. 1996 Nov;17(11):511-6. doi: 10.1016/0167-5699(96)30059-5.

Abstract

X-linked hyper-IgM syndrome (X-HIM) is an immunodeficiency caused by mutations in the gene encoding the CD40 ligand (CD40L). A database (CD40Lbase) of CD40L mutations has now been established, and the resultant information, together with other mutations reported elsewhere in the literature, is presented here.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • CD40 Antigens / genetics*
  • CD40 Ligand
  • Databases, Factual*
  • Genetic Linkage
  • Humans
  • Hypergammaglobulinemia / genetics*
  • Immunoglobulin M / genetics*
  • Ligands
  • Membrane Glycoproteins / genetics*
  • Mutation*
  • X Chromosome*

Substances

  • CD40 Antigens
  • Immunoglobulin M
  • Ligands
  • Membrane Glycoproteins
  • CD40 Ligand