Systemic lupus erythematosus in males. A study of 107 Latin American patients

Medicine (Baltimore). 1996 May;75(3):124-30. doi: 10.1097/00005792-199605000-00002.


Clinical and laboratory features were analyzed in 107 Latin American male patients with systemic lupus erythematosus (SLE) who were compared with a group of 1,209 Latin American female patients with SLE to determine the presence of gender-associated differences. Males had an increased prevalence of renal disease, vascular thrombosis, and the presence of anti-dsDNA antibodies, as well as the use of moderate to high doses of corticosteroids, compared with female SLE patients. Although there was no difference in mortality from all causes, SLE-related mortality was higher in the male group. All these findings are consistent with a more severe disease in Latin American males than in female patients from the same region.

Publication types

  • Comparative Study
  • Multicenter Study
  • Review

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Cause of Death
  • Child
  • Child, Preschool
  • Cohort Studies
  • Cross-Sectional Studies
  • Female
  • Humans
  • Latin America
  • Lupus Erythematosus, Systemic / complications
  • Lupus Erythematosus, Systemic / mortality
  • Lupus Erythematosus, Systemic / physiopathology*
  • Male
  • Middle Aged
  • Severity of Illness Index
  • Sex Characteristics*