Assessment of Mitochondrial Oxidative Phosphorylation in Patient Muscle Biopsies, Lymphoblasts, and Transmitochondrial Cell Lines

Methods Enzymol. 1996;264:484-509. doi: 10.1016/s0076-6879(96)64044-0.

Authors

I A Trounce¹, Y L Kim, A S Jun, D C Wallace

Affiliation

¹ Department of Genetics and Molecular Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

PMID: 8965721
DOI: 10.1016/s0076-6879(96)64044-0

MeSH terms

Biopsy
Cell Line
Cells, Cultured
Citrate (si)-Synthase / metabolism
Culture Techniques / methods
Electron Transport Complex II
Electron Transport Complex III / metabolism
Electron Transport Complex IV / metabolism
Humans
Kinetics
Lymphocytes / metabolism*
Mitochondria / metabolism*
Mitochondria, Muscle / metabolism*
Multienzyme Complexes / metabolism
Muscle, Skeletal / metabolism*
Muscle, Skeletal / pathology
Myofibrils / pathology
NAD(P)H Dehydrogenase (Quinone) / metabolism
Osteosarcoma
Oxidative Phosphorylation*
Oxidoreductases / metabolism
Polarography / methods
Succinate Dehydrogenase / metabolism
Tumor Cells, Cultured

Substances

Multienzyme Complexes
Oxidoreductases
Electron Transport Complex II
Succinate Dehydrogenase
NAD(P)H Dehydrogenase (Quinone)
Electron Transport Complex IV
Citrate (si)-Synthase
Electron Transport Complex III