Nerve root hypertrophy as the cause of lumbar stenosis in chronic inflammatory demyelinating polyradiculoneuropathy

Muscle Nerve. 1996 Jul;19(7):892-6. doi: 10.1002/(SICI)1097-4598(199607)19:7<892::AID-MUS12>3.0.CO;2-L.


Two patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) developed signs of lumbar stenosis. Radiologic, intraoperative, and pathologic findings demonstrated lumbar stenosis secondary to nerve root hypertrophy. This syndrome has been demonstrated in hereditary but not acquired demyelinating neuropathies. CIDP should be considered in the differential diagnosis of sciatica and nerve root hypertrophy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Chronic Disease
  • Demyelinating Diseases / complications*
  • Demyelinating Diseases / pathology*
  • Humans
  • Hypertrophy
  • Lumbosacral Region
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Polyradiculoneuropathy / complications*
  • Polyradiculoneuropathy / pathology*
  • Spinal Nerve Roots / diagnostic imaging
  • Spinal Nerve Roots / pathology*
  • Spinal Stenosis / diagnostic imaging
  • Spinal Stenosis / etiology*
  • Spinal Stenosis / pathology
  • Tomography, X-Ray Computed