The cloned gene, Xa21, confers resistance to multiple Xanthomonas oryzae pv. oryzae isolates in transgenic plants

Mol Plant Microbe Interact. 1996 Dec;9(9):850-5. doi: 10.1094/mpmi-9-0850.


The cloned rice gene, Xa21, confers resistance to multiple pathogen isolates of Xanthomonas oryzae pv. oryzae in transgenic plants. The resistance phenotype was stably transmitted to T1 progeny and inherited as a single locus. The T1 progeny were tested for resistance to 32 X. oryzae pv. oryzae isolates from eight countries. Both the engineered line and the donor line showed resistance to 29 isolates and susceptibility to three isolates. The identical resistance spectrum of both lines indicates that the presence of a single member of a multigene family, Xa21, is sufficient to confer multi-isolate resistance. The results presented here have important implications for engineering disease resistance in crop plants.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Base Sequence
  • Cloning, Molecular
  • DNA Primers / genetics
  • Genes, Plant*
  • Korea
  • Oryza / genetics*
  • Oryza / microbiology*
  • Phenotype
  • Plants, Genetically Modified / genetics
  • Plants, Genetically Modified / microbiology
  • Polymerase Chain Reaction
  • Xanthomonas / pathogenicity*


  • DNA Primers