Mood disorder and chronic hypercalcemia

J Psychosom Res. 1996 Oct;41(4):343-7. doi: 10.1016/s0022-3999(96)00132-8.


Fifty-five patients with chronic hypercalcemia were compared with test norms, and two comparison groups of orthopedic patients and hypertensive patients on objective and subjective tests of mood. Sixteen percent of the hypercalcemic patients were found to score over the cut-off point for anxiety on the anxiety subsection of the Hospital Anxiety and Depression Scale, and 16% were diagnosed as suffering from depression on the Paykel Clinical Interview for Depression. There were, however, no significant differences between the comparison groups and those with hypercalcemia on the scales used. There has been debate about the management of individuals with hypercalcemia. This study supports a conservative rather than a surgical approach as far as psychological symptoms are concerned.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anxiety Disorders / diagnosis
  • Anxiety Disorders / psychology*
  • Anxiety Disorders / therapy
  • Depressive Disorder / diagnosis
  • Depressive Disorder / psychology*
  • Depressive Disorder / therapy
  • Female
  • Humans
  • Hypercalcemia / diagnosis
  • Hypercalcemia / psychology*
  • Hypercalcemia / therapy
  • Hyperparathyroidism / diagnosis
  • Hyperparathyroidism / psychology
  • Hyperparathyroidism / therapy
  • Male
  • Middle Aged
  • Neurocognitive Disorders / diagnosis
  • Neurocognitive Disorders / psychology*
  • Neurocognitive Disorders / therapy
  • Parathyroid Hormone / blood
  • Patient Care Team
  • Personality Inventory


  • Parathyroid Hormone