Abstract
We identified in Dictyostelium a gene snwA containing a region of similarity to SH2 domains of higher eukaryotes. snwA is homologous to a novel human gene SNW1 and to Bx42 from Drosophila melanogaster, a gene coding for a chromatin binding protein responsive to 20-OH-ecdysone. snwA has one mRNA transcript of an approximate size of 2.5 kb.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Amino Acid Sequence
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Animals
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Chromatin / metabolism
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DNA-Binding Proteins / analysis
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DNA-Binding Proteins / genetics*
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Dictyostelium / genetics*
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Drosophila Proteins*
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Humans
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Molecular Sequence Data
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Nuclear Proteins / chemistry
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Nuclear Proteins / genetics*
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Nuclear Proteins / metabolism
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Protozoan Proteins*
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Sequence Homology, Amino Acid
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src Homology Domains
Substances
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Chromatin
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DNA-Binding Proteins
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Drosophila Proteins
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Nuclear Proteins
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Protozoan Proteins
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SNWA protein, Dictyostelium discoideum
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Bx42 protein, Drosophila
Associated data
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GENBANK/P39736
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GENBANK/T10217
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GENBANK/U43887
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GENBANK/U43960
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GENBANK/X62577
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GENBANK/Z66569