Effect of gold treatment on the progression of erosions in RA patients

Scand J Rheumatol. 1977;6(2):123-7. doi: 10.3109/03009747709095434.


The progressive of erosive X-ray changes over a period of 5-6 years was evaluated in RA patients with a low or high dose of gold during the follow-up period. The "low gold" group included 18 patients whose treatment was discontinued because of side effects at a mean dose of 254 mg of Myocrisin. The "high gold" group included 32 patients who received a mean dose of 1858 mg of Myocrisin. Both the number of eroded joints in the hands and feet and the X-ray stage had deteriorated more in the "low gold" group. The inter-group difference was statistically significant. Thus, gold treatment has a retarding effect on the progression of erosions in RA patients.

MeSH terms

  • Adolescent
  • Adult
  • Arthritis, Rheumatoid / diagnostic imaging
  • Arthritis, Rheumatoid / drug therapy*
  • Dose-Response Relationship, Drug
  • Female
  • Follow-Up Studies
  • Gold / administration & dosage
  • Gold / therapeutic use*
  • Humans
  • Male
  • Middle Aged
  • Radiography


  • Gold