Differences in clinical manifestations of genital chlamydial infections related to serovars

Genitourin Med. 1996 Aug;72(4):261-5.


Objectives: To study the association of serovars of Chlamydia trachomatis with clinical manifestations of genital tract infection and socio-demographic characteristics.

Methods: In 1986-88 the C trachomatis isolates from 159 heterosexual men and 116 women attending a sexually transmitted disease (STD) clinic were collected and typed accordingly. A medical history was recorded, a physical examination took place and samples were taken for laboratory diagnostics.

Results: Serovars E, F and D were the most common for both men (75%) and women (67%). Men infected with serovars of the C-complex had more often a history of STD (p = 0.06). The opposite was demonstrated in women (p = 0.07). In addition, women younger than 18 years at first intercourse were more often infected with C-complex serovars (p = 0.05). For men, the serovars F/G less often produced symptoms of urethral discharge (p = 0.01) than the serovars of the B-complex and C-complex and were less often associated with the presence of 10 or more leukocytes in a Gram-stained smear (p = 0.04).

Conclusions: In this study, infections with serovars F and G caused less obvious symptoms and signs of inflammation in men; in women no differences were found in the clinical manifestation of infections with different serovars.

MeSH terms

  • Adolescent
  • Adult
  • Chlamydia Infections / epidemiology
  • Chlamydia Infections / pathology*
  • Chlamydia trachomatis / classification*
  • Female
  • Female Urogenital Diseases / epidemiology
  • Female Urogenital Diseases / microbiology
  • Female Urogenital Diseases / pathology
  • Genital Diseases, Female / epidemiology
  • Genital Diseases, Female / microbiology
  • Genital Diseases, Female / pathology
  • Humans
  • Male
  • Male Urogenital Diseases
  • Netherlands / epidemiology
  • Prevalence
  • Regression Analysis
  • Sexual Behavior
  • Urologic Diseases / epidemiology
  • Urologic Diseases / microbiology
  • Urologic Diseases / pathology