Effects of guizhi-fuling-wan on male infertility with varicocele

Am J Chin Med. 1996;24(3-4):327-31. doi: 10.1142/S0192415X96000396.


Thirty-seven infertile patients with varicocele were treated with Guizhi-Fuling-Wan (7.5 g/day) for at least 3 months. Before and after the administration, semen qualities such as sperm concentration and motility were examined, and the varicocele was graded. A varicocele disappearance rate of 80% was obtained with 40 out of 50 varicocele, and improvement of sperm concentration and motility were found in 71.4% and 62.1% of patients, respectively. From these results, Guizhi-Fuling-Wan is considered to be effective for circulation disorders in varicocele as well as semen quality.

MeSH terms

  • Adult
  • Humans
  • Infertility, Male / drug therapy*
  • Male
  • Medicine, Chinese Traditional*
  • Varicocele / drug therapy*