The purposes of this study were to develop and test an implantable interface that could be used for repeated temporary electrical connections between implanted stimulating and recording devices and external equipment. The implantable multi-use interface (TIMI) consists of an implanted set of connectors and temporary percutaneous leads. The connector(s) and attached devices are implanted during a sterile surgery. For each experimental session, a percutaneous lead is introduced into each connector with a hypodermic needle. The external ends of the percutaneous leads are then connected to the desired equipment. After the session is finished, the percutaneous leads are removed. TIMIs have been used successfully with nerve cuff stimulating electrodes, a tendon force transducer and an electromyography electrode, and have been implanted with nerve cuffs for up to 14 weeks without failure. The advantages of the TIMI over the standard backpack connector include: (1) the internal location of the connector reduces the risk that the animal will damage the connector and (2) the temporary and relatively controlled nature of the percutaneous connection reduces the risk of infection associated with permanent percutaneous leads. The TIMI provides an inexpensive, simple and reliable electrical connection between implanted devices and external equipment.