Vasculyne, a new cytotoxic acetylenic alcohol from the marine sponge Cribrochalina vasculum

J Nat Prod. 1996 Jan;59(1):88-9. doi: 10.1021/np9600199.

Abstract

A new C43 acetylenic alcohol, vasculyne (1), was isolated by cytotoxicity-guided fractionation of the Caribbean sponge Cribrochalina vasculum. The structure of 1 was determined by spectroscopic methods.

MeSH terms

  • Animals
  • Antineoplastic Agents / isolation & purification*
  • Antineoplastic Agents / pharmacology
  • Chromatography, High Pressure Liquid
  • Drug Screening Assays, Antitumor
  • Fatty Alcohols / isolation & purification*
  • Fatty Alcohols / pharmacology
  • Porifera / chemistry*
  • Tumor Cells, Cultured

Substances

  • Antineoplastic Agents
  • Fatty Alcohols
  • vasculyne