Actin-based organelle movement

Experientia. 1996 Dec 15;52(12):1117-22. doi: 10.1007/BF01952110.


Evidence for actin-dependent organelle movement was first obtained from studies of cytoplasmic streaming in plants. These studies, together with cell-free organelle motility studies and biophysical analyses of muscle myosin, support a model whereby organelle-associated motor molecules utilize the energy of adenosine triphosphate binding and hydrolysis to drive movement along F-actin tracks. Recent studies indicate that this mechanism for organelle movement may be responsible for organelle and vesicle movement during secretion, endocytosis and mitochondrial inheritance in a variety of eukaryotes.

Publication types

  • Review

MeSH terms

  • Actins / pharmacology
  • Cytoplasmic Streaming / physiology
  • Endocytosis
  • Mitochondria / genetics
  • Mitochondria / metabolism
  • Models, Molecular
  • Organelles / metabolism*
  • Plants / metabolism
  • Water-Electrolyte Balance / physiology


  • Actins