Pain during arterial puncture

Chest. 1996 Dec;110(6):1443-5. doi: 10.1378/chest.110.6.1443.


Study objective: To quantify the level of pain reported by patients during arterial puncture with or without local anesthesia, and to compare the results with levels reported for venous puncture.

Design: Double-blind study of puncture with and without local anesthesia.

Setting: Pulmonary function laboratory, department of pneumology.

Patients: We studied 270 consecutive patients undergoing arterial puncture divided into two groups. In group A (n = 210), we assessed level of pain with and without local anesthesia and with placebo. In group B (n = 60), we compared pain of arterial and venous puncture.

Interventions: The arterial puncture was performed in the radial artery; venous puncture was in the median basilic vein.

Measurements and results: The pain was quantified on a visual analog scale (10 cm). Mean level of pain for all arterial punctures without anesthesia or placebo was slight to moderate (3.01 +/- 1.94 cm). Subcutaneous anesthetic infiltration before arterial puncture significantly reduced pain by more than 50%, to 1.50 +/- 1.54 cm, a level that was significantly lower than the pain level reported after conventional venous puncture (1.80 +/- 1.10 cm). The pain reported by patients who received no anesthesia was not significantly different (p = 0.45) from that perceived by those who received subcutaneous infiltration of saline solution (placebo).

Conclusions: Arterial puncture with prior infiltration of local anesthetic is the least painful procedure among those studied. Use of local anesthesia is indicated whenever conventional arterial puncture is required.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anesthesia, Local*
  • Arteries*
  • Blood Specimen Collection
  • Double-Blind Method
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pain / etiology*
  • Pain / prevention & control
  • Pain Measurement
  • Prospective Studies
  • Punctures / adverse effects*
  • Veins