Astrocytes are one of the main target cells for pituitary adenylate cyclase-activating polypeptide in the central nervous system. Astrocytes are very heterogeneous regarding both basal movement of intracellular free calcium ([Ca2+]i) and the [Ca2+]i response to PACAP at a single cell level

Ann N Y Acad Sci. 1996 Dec 26;805:613-9. doi: 10.1111/j.1749-6632.1996.tb17529.x.
No abstract available

MeSH terms

  • Animals
  • Animals, Newborn
  • Astrocytes / cytology
  • Astrocytes / drug effects
  • Astrocytes / metabolism*
  • Brain / metabolism*
  • Cells, Cultured
  • Cyclic AMP / metabolism*
  • Kinetics
  • Neurons / cytology
  • Neurons / drug effects
  • Neurons / metabolism*
  • Neuropeptides / pharmacology*
  • Neurotransmitter Agents / pharmacology
  • Pituitary Adenylate Cyclase-Activating Polypeptide
  • Pituitary Gland / drug effects
  • Pituitary Gland / metabolism
  • Rats
  • Rats, Sprague-Dawley

Substances

  • Adcyap1 protein, rat
  • Neuropeptides
  • Neurotransmitter Agents
  • Pituitary Adenylate Cyclase-Activating Polypeptide
  • Cyclic AMP