Psoriasis of the nails associated with disability in a large number of patients: results of a recent interview with 1,728 patients

Dermatology. 1996;193(4):300-3. doi: 10.1159/000246274.


Background and objective: Occurrence rates of clinical features of nail psoriasis vary considerably in the literature. Little information is available on subjective complaints of patients affected by psoriasis of the nails.

Method: Interviews with 1,728 psoriatic patients concerning their nail changes and complaints are reviewed.

Results: The results indicate that pitting and deformation are the most common clinical aberrations in psoriatic nails, with a positive association between the duration of skin lesions and nail psoriasis. No relation was found between age and nail psoriasis in this group. Remarkably, 51.8% of patients suffered from pain-caused by the nail changes, and a large group of patients was restricted in their daily activities, housekeeping and/or profession (58.9, 56.1, 47.9%). Treatment was disappointing: only 19.3% showed marked improvement during treatment.

Conclusion: This indicates that psoriasis of the nails is a more important individual and social-economic problem than previously assumed and that development of new treatments is needed.

Publication types

  • Meta-Analysis
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Disabled Persons
  • Female
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Nails*
  • Netherlands / epidemiology
  • Prognosis
  • Psoriasis / diagnosis
  • Psoriasis / drug therapy
  • Psoriasis / epidemiology*
  • Psoriasis / physiopathology
  • Quality of Life
  • Regression Analysis
  • Risk Factors
  • Sex Distribution
  • Surveys and Questionnaires