Reciprocal 8;14 translocation in EBV-negative B-cell acute lymphocytic leukemia with Burkitt-type cells

Int J Cancer. 1979 Jul 15;24(1):27-33. doi: 10.1002/ijc.2910240106.

Abstract

A cytogenetic study, including prophase-prometaphase chromosome analysis, of a patient with EBV-genome-negative acute lymphocytic leukemia of B-cell type with Burkitt-type cells is presented. All bone-marrow mitoses examined had a 14q+ marker chromosome which was identified as a reciprocal 8;14 translocation of exactly the same type as in Burkitt's lymphoma.

Publication types

  • Case Reports

MeSH terms

  • Antigens, Viral
  • B-Lymphocytes / immunology
  • Bone Marrow / pathology
  • Burkitt Lymphoma / genetics
  • Chromosomes, Human, 13-15*
  • Chromosomes, Human, 6-12 and X*
  • DNA, Viral
  • Epitopes
  • Herpesvirus 4, Human / immunology
  • Humans
  • Leukemia, Lymphoid / genetics*
  • Leukemia, Lymphoid / immunology
  • Leukemia, Lymphoid / microbiology
  • Male
  • Metaphase
  • Middle Aged
  • Nucleic Acid Hybridization
  • Prophase
  • Receptors, Antigen, B-Cell
  • Translocation, Genetic*

Substances

  • Antigens, Viral
  • DNA, Viral
  • Epitopes
  • Receptors, Antigen, B-Cell