Age-dependent correlation of low-back pain and lumbar disc regeneration

Arch Orthop Trauma Surg. 1997;116(1-2):106-7. doi: 10.1007/BF00434112.


The prevalence of lumbar disc degeneration in subjects suffering from low-back pain (n = 207; age range 10-49 years) and in age-matched asymptomatic controls (n = 216) was investigated by magnetic resonance imaging. The percentage of subjects with degenerated discs increased with age; starting from the age of 15 years, this increase was more rapid in subjects with low-back pain. Concurrently, the number of degenerated discs was higher in the pain group than in controls. Lumbar disc degeneration manifests earlier and in a greater percentage of subjects with low-back pain than in asymptomatic controls.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Humans
  • Intervertebral Disc / pathology*
  • Low Back Pain / etiology*
  • Low Back Pain / pathology
  • Lumbar Vertebrae*
  • Middle Aged