Kinetic analysis of biosensor data: elementary tests for self-consistency

Trends Biochem Sci. 1996 Dec;21(12):458-60. doi: 10.1016/s0968-0004(96)20025-8.

Abstract

The validity of the most common kinetic interpretation of biosensor data can be quickly assessed with the aid of two simple tests for self-consistency, requiring only back-of-the-envelope calculations. A search of the recent literature reveals that many published results fail these tests qualitatively.

MeSH terms

  • Biosensing Techniques / standards*
  • Kinetics*
  • Models, Theoretical*
  • Reproducibility of Results