Bmmar1: a basal lineage of the mariner family of transposable elements in the silkworm moth, Bombyx mori

Insect Biochem Mol Biol. Sep-Oct 1996;26(8-9):945-54. doi: 10.1016/s0965-1748(96)00061-6.

Abstract

We describe a transposable element, called Bmmar1, from the genome of the silkworm moth, Bombyx mori. This element has features of the Tc1-mariner superfamily of transposable elements. Bmmar1 was first detected as a fragment in the 5' region of the larval serum protein (BmLSP) gene. Six genomic clones characterized each differed from a consensus sequence by 3-5 insertions and deletions, as well as an average of 2.3% in nucleotide sequence. The genome contains approximately 2400 copies of Bmmar1. Maximum parsimony phylogenetic analysis of the relationship of Bmmar1 and other members of the Tc1-mariner superfamily, based on their encoded transposase amino acid sequences, indicates that it represents a basal lineage of the mariner family. In particular Bmmar1 encodes a D,D37D motif thought to be the catalytic domain of mariner transposases. Bmmar1 considerably increases the known diversity of this widespread family of transposons. A new naming system is proposed for members of the family.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Bombyx / genetics*
  • Consensus Sequence
  • DNA
  • DNA Transposable Elements*
  • Evolution, Molecular
  • Gene Dosage
  • Genes, Insect*
  • Molecular Sequence Data
  • Phylogeny
  • Sequence Homology, Amino Acid
  • Sequence Homology, Nucleic Acid

Substances

  • DNA Transposable Elements
  • DNA

Associated data

  • GENBANK/U43130
  • GENBANK/U43131
  • GENBANK/U43132
  • GENBANK/U43133
  • GENBANK/U43134
  • GENBANK/U43135
  • GENBANK/U47917