The interleukin-1 beta converting enzyme family of cysteine proteases

J Cell Biochem. 1997 Jan;64(1):2-10. doi: 10.1002/(sici)1097-4644(199701)64:1<2::aid-jcb2>3.0.co;2-1.

Abstract

Interleukin-1 beta converting enzyme (ICE) is the first enzyme of a new family of cysteine endoproteinases to be isolated and characterized. An overview of the structure and activity of ICE is outlined together with highlights of salient features common to members of each of the family members.

Publication types

  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Apoptosis / physiology*
  • Binding Sites
  • Caspase 1
  • Cysteine Endopeptidases / chemistry*
  • Cysteine Endopeptidases / genetics
  • Cysteine Endopeptidases / metabolism*
  • Humans
  • Models, Molecular
  • Molecular Sequence Data
  • Phylogeny
  • Protein Conformation
  • Sequence Homology, Amino Acid

Substances

  • Cysteine Endopeptidases
  • Caspase 1