Growth factors in angiogenesis: current interest and therapeutic potential

Mol Med Today. 1997 Jan;3(1):14-23. doi: 10.1016/S1357-4310(96)10048-4.


Angiogenesis, the process of new blood vessel development, is an essential component of the body's physiology and contributes to the pathogenesis of a variety of diseases such as benign and malignant neoplasia and rheumatoid arthritis. Failure of this physiological response is also important in abnormalities of wound healing in diseases such as duodenal ulceration and diabetes. Angiogenesis is controlled by a variety of factors that initiate, control and terminate this complex, multi-stage process. This review covers those factors that are exciting much interest currently and have potential for incorporation into clinical medicine.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Forecasting
  • Growth Substances / physiology*
  • Humans
  • Neovascularization, Pathologic
  • Neovascularization, Physiologic / physiology*


  • Growth Substances