Cognitive function in elderly non-insulin-dependent diabetic patients before and after inpatient treatment for metabolic control

J Diabetes Complications. Jan-Feb 1997;11(1):40-6. doi: 10.1016/1056-8727(95)00106-9.

Abstract

Cognitive function was measured before and after inpatient treatment for metabolic control in 20 elderly patients with non-insulin-dependent diabetes mellitus (NIDDM). Another 20 patients still on the waiting list for this treatment, served as a control group. Glycosylated hemoglobin decreased in both groups. Psychomotor speed and concentration improved only after inpatient treatment (p < 0.01; p < 0.05, respectively). Improved performance was maintained and even enhanced 6 weeks after discharge from inpatient treatment. Performance in concentration tasks correlated with glycosylated hemoglobin (p < 0.05). It is concluded that cognitive deficits in elderly NIDDM patients can be reduced by inpatient treatment, although the benefit of glycemic control was not clearly demonstrated in this study.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Analysis of Variance
  • Attention / physiology
  • Auditory Perception / physiology
  • Blood Glucose / analysis
  • Blood Glucose / metabolism
  • Cognition / physiology*
  • Cohort Studies
  • Diabetes Mellitus, Type 2 / physiopathology*
  • Diabetes Mellitus, Type 2 / therapy*
  • Female
  • Glycated Hemoglobin A / analysis
  • Glycated Hemoglobin A / metabolism
  • Humans
  • Inpatients*
  • Male
  • Middle Aged
  • Psychomotor Performance / physiology
  • Reaction Time / physiology
  • Time Factors
  • Visual Perception / physiology

Substances

  • Blood Glucose
  • Glycated Hemoglobin A