A biochemical perspective of methotrexate neurotoxicity with insight on nonfolate rescue modalities

J Investig Med. 1996 Dec;44(9):522-30.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Acute Disease
  • Adenosine / metabolism
  • Biopterins / metabolism
  • Chronic Disease
  • Folic Acid Antagonists / adverse effects*
  • Homocysteine / metabolism
  • Humans
  • Methotrexate / adverse effects*
  • Nervous System Diseases / chemically induced*
  • Nervous System Diseases / classification
  • Nucleic Acid Synthesis Inhibitors / adverse effects*

Substances

  • Folic Acid Antagonists
  • Nucleic Acid Synthesis Inhibitors
  • Homocysteine
  • Biopterins
  • Adenosine
  • Methotrexate