[Trypsinogen as a modifier of peptidergic influences on the secretion of the gastric and pancreatic glands]

Fiziol Zh Im I M Sechenova. Aug-Sep 1996;82(8-9):87-95.
[Article in Russian]

Abstract

I.v. administration of trypsinogen potentiated the pentagastrin-induced secretion of gastric glands and reduced the leu-enkephalin effect upon them in the fistula dogs. Intraperitoneal administration of trypsinogen enhanced the pepsinogen synthesis by the gastric glands, did not change the hydrolases activity in pancreas homogenate in rats.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Dogs
  • Enkephalin, Leucine / pharmacology
  • Gastric Juice / chemistry
  • Gastric Juice / drug effects
  • Gastric Juice / metabolism
  • Gastric Mucosa / drug effects*
  • Gastric Mucosa / metabolism
  • Pancreas / drug effects*
  • Pancreas / metabolism
  • Pentagastrin / pharmacology
  • Rats
  • Receptors, Peptide / drug effects*
  • Receptors, Peptide / physiology
  • Stimulation, Chemical
  • Trypsinogen / pharmacology*

Substances

  • Receptors, Peptide
  • Enkephalin, Leucine
  • Trypsinogen
  • Pentagastrin