Chromatographic analysis of water and wine samples for phenolic compounds released from food-contact epoxy resins

J Chromatogr Sci. 1997 Feb;35(2):57-62. doi: 10.1093/chromsci/35.2.57.


Food-contact epoxy resins can release phenolic compounds such as phenol, m-cresol, bisphenol F, bisphenol A, 4-tert-butylphenol, bisphenol F diglycidyl ether (BFDGE), and bisphenol A diglycidyl ether (BADGE) into foodstuffs. A validated high-performance liquid chromatographic method with fluorometric detection is described for the simultaneous analysis of these compounds in wine and mineral water. Sample preparation by solid-liquid extraction enables detection limits of 2.5 micrograms/L in wine and 0.25 microgram/L in mineral water to be achieved. Recovery rates are close to 100%, except for BFDGE and BADGE (around 60% in wine and 75% in mineral water).

MeSH terms

  • Chromatography, High Pressure Liquid / methods*
  • Epoxy Resins / chemistry*
  • Food*
  • Phenols / analysis*
  • Sensitivity and Specificity
  • Spectrometry, Fluorescence
  • Water / analysis*
  • Wine / analysis*


  • Epoxy Resins
  • Phenols
  • Water