Origin, Maturation and Antigen Presenting Function of Dendritic Cells

Curr Opin Immunol. 1997 Feb;9(1):10-6. doi: 10.1016/s0952-7915(97)80153-7.

Abstract

Dendritic cells are cells specialized for antigen capture, migration and T cell stimulation. Recent advances have been made in understanding their origin, their heterogeneity, the mechanism of antigen uptake, and the signals that induce their migration and maturation into immunostimulatory antigen-presenting cells. Dendritic cells represent the natural adjuvants for T cell responses and their therapeutic exploitation in the near future is foreseen.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Antigen Presentation*
  • Cell Differentiation / immunology
  • Dendritic Cells / cytology*
  • Dendritic Cells / immunology*
  • Humans