The Eph family in retinal axon guidance

Curr Opin Neurobiol. 1997 Feb;7(1):75-80. doi: 10.1016/s0959-4388(97)80123-7.

Abstract

The continued functional characterization of Eph-related receptors and ligands has provided further information toward an understanding of the mechanisms controlling the retinotectal projection. Recent in vivo analyses have strengthened the idea that Engrailed defines the positional identity of the tectum along the anteroposterior axis, possibly by regulating the expression of Eph family members.

Publication types

  • Review

MeSH terms

  • Animals
  • Axons / physiology*
  • Ephrin-A2
  • Ephrin-B2
  • Membrane Proteins / physiology*
  • Proteins / physiology*
  • Retina / physiology*
  • Superior Colliculi / physiology
  • Visual Pathways / physiology*

Substances

  • Ephrin-A2
  • Ephrin-B2
  • Membrane Proteins
  • Proteins