Primary epithelioid angiosarcoma of the lung presenting as pulmonary hemorrhage

Hum Pathol. 1997 Mar;28(3):383-5. doi: 10.1016/s0046-8177(97)90140-4.


Pulmonary angiosarcomas are usually secondary tumors, and only a few primary cases have been described. We report a unique case of epithelioid angiosarcoma arising in the lungs as a bilateral multinodular infiltrate and presenting as pulmonary hemorrhage. Because of its epithelioid histology, this tumor may resemble a carcinoma, also staining positively for keratin markers. Therefore, unless the diagnosis of epithelioid angiosarcoma is considered and endothelial markers used, the diagnosis of epithelioid angiosarcoma may be overlooked at this site.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antigens, CD34 / analysis
  • Epithelioid Cells / pathology*
  • Fatal Outcome
  • Hemangiosarcoma / chemistry
  • Hemangiosarcoma / diagnosis*
  • Hemangiosarcoma / pathology
  • Hemorrhage / diagnosis*
  • Humans
  • Lung Diseases / diagnosis*
  • Lung Neoplasms / chemistry
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / pathology
  • Male
  • Tomography, X-Ray Computed


  • Antigens, CD34