[The isolation of a transfer factor of the delayed-hypersensitivity type to the antigenic substances of Staphylococcus aureus in guinea pigs]

O H Holieva; T A Liubchenko; L S Kholodna; A Iu Vershihora

[The isolation of a transfer factor of the delayed-hypersensitivity type to the antigenic substances of Staphylococcus aureus in guinea pigs]

Fiziol Zh (1994). 1996;42(5-6):58-65.

[Article in Ukrainian]

Authors

O H Holieva, T A Liubchenko, L S Kholodna, A Iu Vershihora

PMID: 9044813

Abstract

Immunoactivating effects of guinea pig's staphylococcal Transfer factor (TF) were studied in homologous and heterologous (human leukocytes) systems. In vivo (skin tests) and in vitro (Inhibition of leukocytes migration) tests showed that our TF is able to activate intact as well as sensibilized cells. Antigen-specific properties of TF also were showed.

Publication types

English Abstract

MeSH terms

Animals
Antigens, Bacterial / immunology*
Cell Migration Inhibition
Epitopes / immunology
Guinea Pigs
Humans
Hypersensitivity, Delayed / immunology*
Immunization
Leukocytes / immunology
Skin Tests / statistics & numerical data
Staphylococcus aureus / immunology*
Transfer Factor / administration & dosage
Transfer Factor / immunology
Transfer Factor / isolation & purification*

Substances

Antigens, Bacterial
Epitopes
Transfer Factor