Hypertension in pregnancy: current concepts of preeclampsia

Annu Rev Med. 1997:48:115-27. doi: 10.1146/annurev.med.48.1.115.

Abstract

Hypertensive disorders (gestational hypertension, preeclampsia, chronic hypertension, superimposed preeclampsia) are the most common medical complications of pregnancy and constitute a major cause of maternal and perinatal morbidity and mortality. Prediction of those women destined to develop preeclampsia remains elusive. The benefits of calcium supplementation for prevention of preeclampsia are encouraging; however, the definitive study is not yet complete. Aspirin therapy for high-risk has not been helpful; results of therapy for high-risk women are pending. More experience is being gained with antihypertensive therapy and expectant management in severe preeclampsia. Conservative management of severe preeclampsia, when performed in a tertiary care center, may benefit a select group of women and their fetuses.

Publication types

  • Review

MeSH terms

  • Antihypertensive Agents / adverse effects
  • Antihypertensive Agents / therapeutic use*
  • Combined Modality Therapy
  • Eclampsia / drug therapy
  • Eclampsia / etiology
  • Eclampsia / mortality
  • Female
  • Humans
  • Infant, Newborn
  • Pre-Eclampsia / drug therapy*
  • Pre-Eclampsia / etiology
  • Pre-Eclampsia / mortality
  • Pregnancy
  • Pregnancy Outcome
  • Pregnancy, High-Risk
  • Survival Rate
  • Treatment Outcome

Substances

  • Antihypertensive Agents