The complete cDNA coding sequence and tissue-specific expression of the mouse laminin alpha 4 chain

Matrix Biol. 1996 Dec;15(6):433-7. doi: 10.1016/s0945-053x(96)90162-6.

Abstract

The full-length cDNA coding sequence is presented for the mouse laminin alpha 4 chain. Comparison of the encoded amino acid sequence with human laminin alpha 4 shows 88.3% identity. Northern blot analysis shows that mouse laminin alpha 4 is strongly expressed in heart, lung and skeletal muscle, with only limited expression in brain, spleen, liver, kidney and testes.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Blotting, Northern
  • DNA Primers
  • DNA, Complementary
  • Humans
  • Laminin / biosynthesis*
  • Laminin / chemistry
  • Male
  • Mice
  • Molecular Sequence Data
  • Organ Specificity
  • Polymerase Chain Reaction
  • Sequence Homology, Amino Acid

Substances

  • DNA Primers
  • DNA, Complementary
  • LAMA4 protein, human
  • Lama4 protein, mouse
  • Laminin

Associated data

  • GENBANK/U69176