Synthesis of some 1-(2-arylvinyl)-3-arylpyrazino[1,2-a]benzimidazole derivatives and their antimicrobial activities

Farmaco. 1996 Dec;51(12):825-7.

Abstract

Some 1-(2-arylvinyl)-3-arylhyrazino[1,2-a]benzimidazole derivatives were synthesized, their structures were elucidated, and their antibacterial and antifungal activities were examined. None of the compounds proved to be sufficiently active.

MeSH terms

  • Anti-Bacterial Agents
  • Anti-Infective Agents / chemical synthesis*
  • Anti-Infective Agents / pharmacology
  • Antifungal Agents / chemical synthesis
  • Antifungal Agents / pharmacology
  • Bacteria / drug effects
  • Benzimidazoles / chemical synthesis*
  • Benzimidazoles / pharmacology
  • Candida albicans / drug effects
  • Magnetic Resonance Spectroscopy
  • Microbial Sensitivity Tests
  • Pyrazines / chemical synthesis*
  • Pyrazines / pharmacology
  • Spectrophotometry, Infrared

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antifungal Agents
  • Benzimidazoles
  • Pyrazines