Effects of acute alcohol ingestion on heart rate variability in patients with documented coronary artery disease and stable angina pectoris

Am J Cardiol. 1997 Feb 15;79(4):487-91. doi: 10.1016/s0002-9149(96)00790-4.


The effects of acute alcohol intake (ethanol blood concentration 1.3 +/- 0.4%) on heart rate variability were evaluated with 24-hour Holter recordings in 20 patients with stable coronary artery disease in a juice-controlled experiment. In the frequency domain analysis, the high-, low-, and very low frequency components were significantly decreased after alcohol: these changes last longer than the elimination of alcohol.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Adult
  • Aged
  • Angina Pectoris / physiopathology*
  • Coronary Disease / physiopathology*
  • Electrocardiography
  • Electrocardiography, Ambulatory
  • Ethanol / blood
  • Ethanol / pharmacology*
  • Exercise Test
  • Female
  • Heart Rate / drug effects*
  • Humans
  • Male
  • Middle Aged


  • Ethanol