A Polycomb-group Gene Regulates Homeotic Gene Expression in Arabidopsis

Nature. 1997 Mar 6;386(6620):44-51. doi: 10.1038/386044a0.

Abstract

Cell fate is determined when the commitment of cells to a particular fate is autonomously maintained, irrespective of their environment. In Drosophila, fate determination is maintained through the action of the Polycomb-group and trithorax-group genes, which are required so that states of homeotic gene activity are inherited through cell division. It is shown here that the CURLY LEAF gene of Arabidopsis is necessary for stable repression of a floral homeotic gene and encodes a protein with homology to the product of the Polycomb-group gene Enhancer of zeste. We suggest that Polycomb-group genes have a similar role in fate determination in plants and animals.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • AGAMOUS Protein, Arabidopsis
  • Amino Acid Sequence
  • Animals
  • Arabidopsis / genetics*
  • Arabidopsis / ultrastructure
  • Arabidopsis Proteins*
  • Cell Lineage / genetics
  • Cloning, Molecular
  • DNA Transposable Elements
  • DNA-Binding Proteins / genetics
  • Drosophila / genetics
  • Drosophila Proteins*
  • Gene Expression Regulation
  • Genes, Homeobox*
  • Genes, Regulator*
  • Homeodomain Proteins / genetics*
  • In Situ Hybridization
  • Insect Proteins / genetics
  • Molecular Sequence Data
  • Mutagenesis, Insertional
  • Mutation
  • Nuclear Proteins / genetics
  • Plant Leaves / ultrastructure
  • Plant Proteins / genetics*
  • Polycomb Repressive Complex 2
  • Repressor Proteins*
  • Sequence Homology, Amino Acid

Substances

  • AGAMOUS Protein, Arabidopsis
  • Arabidopsis Proteins
  • CURLY LEAF protein, Arabidopsis
  • DNA Transposable Elements
  • DNA-Binding Proteins
  • Drosophila Proteins
  • Homeodomain Proteins
  • Insect Proteins
  • Nuclear Proteins
  • Plant Proteins
  • Repressor Proteins
  • E(z) protein, Drosophila
  • Polycomb Repressive Complex 2

Associated data

  • GENBANK/Y10580