Effects of Panax Ginseng C.A. Meyer saponins on male fertility

Panminerva Med. 1996 Dec;38(4):249-54.


Sixty-six patients have been treated with Panax Ginseng C.A. Meyer extract, of whom 30 oligoastenospermic sine causa (group A), 16 oligoastenospermic with idiopathic varicocele (group B). Twenty age-matched volunteers were used as controls (group C). Use of Panax Ginseng extract showed an increase in spermatozoa number/ml and progressive oscillating motility, an increase in plasma total and free testosterone, DHT, FSH and LH levels, but a decrease in mean PRL. It is suggested that ginsenosides may have an effect at different levels of the hypothalamus-pituitary-testis axis.

MeSH terms

  • Adult
  • Fertility / drug effects*
  • Humans
  • Male
  • Middle Aged
  • Panax*
  • Plant Extracts / therapeutic use*
  • Plants, Medicinal*
  • Saponins / therapeutic use*


  • Plant Extracts
  • Saponins