Cutaneous epithelioid angiosarcoma: a potential diagnostic trap for cytopathologists

Diagn Cytopathol. 1997 Feb;16(2):160-6; discussion 166-7. doi: 10.1002/(sici)1097-0339(199702)16:2<160::aid-dc14>;2-k.


We report on the cytologic features of a rare case of cutaneous epithelioid angiosarcoma of the scalp occurring in a 65-yr-old Chinese male. The prominent epithelioid features may cytologically mimic poorly-differentiated carcinoma, malignant melanoma, and even epithelioid sarcoma. Recognition of subtle cytologic features of vasoproliferation, immunohistochemical demonstration of endothelial markers, and ultrastructural examination are necessary before a final conclusion may be drawn.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cytodiagnosis
  • Cytoplasm / ultrastructure
  • Epithelioid Cells / pathology*
  • Epithelioid Cells / ultrastructure
  • Hemangiosarcoma / diagnosis*
  • Hemangiosarcoma / pathology
  • Humans
  • Male
  • Microscopy, Electron
  • Skin Neoplasms / diagnosis*
  • Skin Neoplasms / pathology