The size of the horizontal cell receptive fields adapts to the stimulus in the light adapted goldfish retina

Vision Res. 1996 Dec;36(24):4105-19. doi: 10.1016/s0042-6989(96)00143-5.


In this study the dynamic properties of goldfish horizontal cell (HC) receptive fields were evaluated. The size of HC receptive fields increases up to about 60 msec after stimulus onset, and then reduces to a smaller end value. They can therefore not adequately be described by the cable equation. Estimates of the length constant of the HC network based on the sustained responses are about 43% smaller than those based on the initial part of the response. This difference can be accounted for by feedback connections from HCs to cones because negative feedback reduces the receptive field size. The implication is that HCs are strongly coupled when the retina is stimulated more or less homogeneously but that they partly uncouple from the rest of the HC network when they are stimulated differently than the rest of the retina. The HCs thus generate a feedback signal based on the "local" stimulus properties. The size of the HC receptive fields depends on the spatial detail of the stimulus.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptation, Ocular / physiology*
  • Animals
  • Feedback
  • Goldfish / physiology*
  • Membrane Potentials
  • Models, Neurological*
  • Photic Stimulation
  • Retina / cytology*
  • Retina / physiology
  • Retina / radiation effects
  • Retinal Cone Photoreceptor Cells / physiology