Reproducibility of operator processing for radiation dosimetry

Nucl Med Biol. 1997 Jan;24(1):77-83. doi: 10.1016/s0969-8051(97)00178-9.


Reproducibility of operator processing for radiation dose and biological half-life was assessed for radioimmunotherapy. Mean coefficient of variation for intra-operator consecutive processing and for inter-operator processing was less than 15% for all tissues. The mean coefficient of variation for intraoperator processing over 2 wk or inter-operator processing comparing an experienced and less experienced operator was generally greater, and particularly so for tumors. Satisfactory reproducibility was achievable using visual determination of regions of interests after 80 h of training.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Breast Neoplasms / radiotherapy
  • Copper Radioisotopes / pharmacokinetics
  • Humans
  • Lymphoma, Non-Hodgkin / radiotherapy
  • Observer Variation
  • Phantoms, Imaging*
  • Radiation Monitoring
  • Radioimmunotherapy / instrumentation*
  • Radiotherapy Dosage*
  • Reproducibility of Results


  • Copper Radioisotopes