Defining the skeletal elements

Curr Biol. 1997 Feb 1;7(2):R104-7. doi: 10.1016/s0960-9822(06)00049-2.


A recent study of mice carrying different combinations of mutations in the genes for two bone morphogenetic factors (BMPs), BMP5 and GDF5, indicates that BMPs have specific and synergistic functions in the regulation of skeleton development.

Publication types

  • Review

MeSH terms

  • Animals
  • Bone Development*
  • Bone Morphogenetic Proteins / genetics
  • Bone Morphogenetic Proteins / physiology*
  • Bone and Bones / abnormalities
  • Growth Substances / physiology*
  • Humans
  • Mice
  • Mice, Mutant Strains
  • Morphogenesis
  • Signal Transduction


  • Bone Morphogenetic Proteins
  • Growth Substances