Histone acetyltransferases in control

Curr Biol. 1997 Feb 1;7(2):R82-4. doi: 10.1016/s0960-9822(06)00042-x.

Abstract

Several transcriptional regulators have been found to act as enzymes that acetylate histones. The targeted post-translational modification of histones within regulatory nucleoprotein complexes provides an attractive mechanism for controlling transcription within a chromatin environment.

Publication types

  • Review

MeSH terms

  • Acetyltransferases / metabolism*
  • Animals
  • Chromatin / physiology*
  • Gene Expression Regulation
  • Histone Acetyltransferases
  • Histone Deacetylases / metabolism
  • Models, Biological
  • Saccharomyces cerevisiae / metabolism
  • Saccharomyces cerevisiae Proteins*
  • Transcription, Genetic*
  • Transcriptional Activation

Substances

  • Chromatin
  • Saccharomyces cerevisiae Proteins
  • Acetyltransferases
  • Histone Acetyltransferases
  • Histone Deacetylases